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N-ethyl-Hexedrone is a stimulant compound which is a derivative of cathinone group of chemicals and was developed early in 2011 and it is the result of a great deal of work elucidating the quantitative structure–activity relationship of the scaffold. The team looked for the key moieties which resulted in creating a compound which acts as NDRI(norepinephrine-dopamine reuptake inhibitor) with higher selectivity for dopamine transporter than norepinephrine transporter). It is also possible for this chemical to have low affinity to serotonin transorter, but for amounts needed to succesful research this effect can be skipped. Another function of N-Ethyl-Hexedrone(Ethyl-Hex, NEH)is that it functions as a local anaesthetic with effectivnes similar to Pentedrone and a-PVP. The duration of analgesia ranges from 30 to 60 minutes and only 40mg of N-Ethyl-Hexedrone is needed for succesful research. The duration of chemical reaction in laboratory starts after 2 to 5 minutes (depending of used labgear) with full results presented after 20-25, minutes which remain constant for 1-2 hours.